Installation | Overview of the workflow | Loading PKML models | Specifying model parameters for analysis | Specifying model outputs for analysis | Running one-at-a-time analyses (local and uncertainty analysis) | Running the Morris (global) sensitivity method | Running variance-based Global Sensitivity Analyses (Sobol and EFAST) | Using the graphical user interface and R script generation | Next steps
Package: ospsuite.globalsensitivity 1.0.0
Abdullah Hamadeh
ospsuite.globalsensitivity: Open Systems Pharmacology Global Sensitivity Package
A global sensitivity analysis for Open Systems Pharmacology models.
Authors:
ospsuite.globalsensitivity_1.0.0.tar.gz
ospsuite.globalsensitivity_1.0.0.zip(r-4.7)ospsuite.globalsensitivity_1.0.0.zip(r-4.6)ospsuite.globalsensitivity_1.0.0.zip(r-4.5)
ospsuite.globalsensitivity_1.0.0.tgz(r-4.6-any)ospsuite.globalsensitivity_1.0.0.tgz(r-4.5-any)
ospsuite.globalsensitivity_1.0.0.tar.gz(r-4.7-any)ospsuite.globalsensitivity_1.0.0.tar.gz(r-4.6-any)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
ospsuite.globalsensitivity/json (API)
| # Install 'ospsuite.globalsensitivity' in R: |
| install.packages('ospsuite.globalsensitivity', repos = c('https://open-systems-pharmacology.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/open-systems-pharmacology/ospsuite.globalsensitivity/issues
Pkgdown/docs site:https://www.open-systems-pharmacology.org
Last updated from:61bddd50b2 (on v1.0.0). Checks:4 ERROR, 1 OK, 3 WARNING, 1 FAIL. Indexed: yes.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| linux-devel-x86_64 | ERROR | 249 | ||
| source / vignettes | OK | 403 | ||
| linux-release-x86_64 | ERROR | 226 | ||
| macos-release-arm64 | ERROR | 124 | ||
| macos-oldrel-arm64 | ERROR | 150 | ||
| windows-devel | WARNING | 255 | ||
| windows-release | WARNING | 187 | ||
| windows-oldrel | WARNING | 123 | ||
| wasm-release | FAIL | 238 |
Exports:distributiongenerateEFASTBarGraphgenerateMorrisPlotgenerateSobolBarGraphgenerateTornadoPlotgetContourPlotLogNormalDistributionLogUniformDistributionNormalDistributionrunEFASTrunGUIrunMorrisrunSobolrunSUSAOutputSAParameterUniformDistribution
Dependencies:backportsbase64encbitbit64bslibcachemcheckmateclicliprcommonmarkcowplotcpp11crayoncurldata.tabledeldirdigestdplyrevaluatefarverfastmapfitdistrplusfontawesomefsgenericsggh4xggnewscaleggplot2ggtextgluegridtextgtablehighrhmshtmltoolshtmlwidgetshttpuvinterpisobandjpegjquerylibjsonliteknitrlabelinglaterlatticelifecyclelitedownloggermagrittrmarkdownMASSMatrixmemoisemimeopenxlsxospsuiteospsuite.plotsospsuite.utilsotelpatchworkpillarpkgconfigpngprettyunitsprogresspromisespurrrR6randtoolboxrappdirsRColorBrewerRcppRcppEigenreadrrlangrmarkdownrngWELLrSharpS7sassscalesshinyshinyjsshinyTreesourcetoolsstringistringrsurvivaltibbletictoctidyrtidyselecttinytextlftzdbutf8vctrsviridisLitevroomwithrwritexlxfunxml2xtableyamlzip
Getting started
Last update: 2026-06-25
Started: 2026-06-25
Mathematical overview of variance-based methods
Mathematical derivation | Computation of variance-based sensitivity indices | Homma & Saltelli (Sobol) | EFAST | References
Last update: 2026-06-25
Started: 2026-06-25
Midazolam DDI example
Background | Parameters analyzed | Loading the package and simulations | Specifying the input parameters | Specifying the model output | Running the sensitivity analyses | Interpreting the results
Last update: 2026-06-25
Started: 2026-06-25
UV filter formulation example
Parameters analyzed | Loading the package and simulation | Specifying the input parameters | Specifying the model output | Running the sensitivity analyses | Interpreting the results
Last update: 2026-06-25
Started: 2026-06-25
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| distribution | distribution |
| generateEFASTBarGraph | generateEFASTBarGraph |
| generateMorrisPlot | generateMorrisPlot |
| generateSobolBarGraph | generateSobolBarGraph |
| generateTornadoPlot | generateTornadoPlot |
| Generate Response Surface Contour Plots for eFAST Results | getContourPlot |
| LogNormalDistribution | LogNormalDistribution |
| LogUniformDistribution | LogUniformDistribution |
| NormalDistribution | NormalDistribution |
| runEFAST | runEFAST |
| runGUI | runGUI |
| runMorris | runMorris |
| runSobol | runSobol |
| runSU | runSU |
| SAOutput | SAOutput |
| SAParameter | SAParameter |
| UniformDistribution | UniformDistribution |
