Package: ospsuite.globalsensitivity 1.0.0

Abdullah Hamadeh

ospsuite.globalsensitivity: Open Systems Pharmacology Global Sensitivity Package

A global sensitivity analysis for Open Systems Pharmacology models.

Authors:Abdullah Hamadeh

ospsuite.globalsensitivity_1.0.0.tar.gz
ospsuite.globalsensitivity_1.0.0.zip(r-4.7-any)ospsuite.globalsensitivity_1.0.0.zip(r-4.6-any)ospsuite.globalsensitivity_1.0.0.zip(r-4.5-any)
ospsuite.globalsensitivity_1.0.0.tgz(r-4.6-any)ospsuite.globalsensitivity_1.0.0.tgz(r-4.5-any)
ospsuite.globalsensitivity_1.0.0.tar.gz(r-4.7-any)ospsuite.globalsensitivity_1.0.0.tar.gz(r-4.6-any)
manual.pdf |manual.html✨
DESCRIPTION |NEWS
card.svg |card.png
ospsuite.globalsensitivity/json (API)

# Install 'ospsuite.globalsensitivity' in R:

install.packages('ospsuite.globalsensitivity', repos = c('https://open-systems-pharmacology.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/open-systems-pharmacology/ospsuite.globalsensitivity/issues

Pkgdown/docs site:https://www.open-systems-pharmacology.org

On CRAN:

4.96 score 3 stars 17 scripts 17 exports 107 dependencies

Last updated from:61bddd50b2 (on v1.0.0). Checks:7 ERROR, 1 OK, 1 FAIL. Indexed: yes.

The latest version of this package failed to build. Look at thebuild logs for more information.

Target	Result	Time	Files	Syslog
linux-devel	ERROR	192
source / vignettes	OK	401
linux-release	ERROR	196
macos-release	ERROR	138
macos-oldrel	ERROR	91
windows-devel	ERROR	162
windows-release	ERROR	162
windows-oldrel	ERROR	153
wasm-release	FAIL	139

Exports:distribution generateEFASTBarGraph generateMorrisPlot generateSobolBarGraph generateTornadoPlot getContourPlot LogNormalDistribution LogUniformDistribution NormalDistribution runEFAST runGUI runMorris runSobol runSU SAOutput SAParameter UniformDistribution

Dependencies:backports base64enc bit bit64 bslib cachem checkmate cli clipr commonmark cowplot cpp11 crayon curl data.table deldir digest dplyr evaluate farver fastmap fitdistrplus fontawesome fs generics ggh4x ggnewscale ggplot2 ggtext glue gridtext gtable highr hms htmltools htmlwidgets httpuv interp isoband jpeg jquerylib jsonlite knitr labeling later lattice lifecycle litedown logger magrittr markdown MASS Matrix memoise mime openxlsx ospsuite ospsuite.plots ospsuite.utils otel patchwork pillar pkgconfig png prettyunits progress promises purrr R6 randtoolbox rappdirs RColorBrewer Rcpp RcppEigen readr rlang rmarkdown rngWELL rSharp S7 sass scales shiny shinyjs shinyTree sourcetools stringi stringr survival tibble tictoc tidyr tidyselect tinytex tlf tzdb utf8 vctrs viridisLite vroom withr writexl xfun xml2 xtable yaml zip

Getting started

Installation | Overview of the workflow | Loading PKML models | Specifying model parameters for analysis | Specifying model outputs for analysis | Running one-at-a-time analyses (local and uncertainty analysis) | Running the Morris (global) sensitivity method | Running variance-based Global Sensitivity Analyses (Sobol and EFAST) | Using the graphical user interface and R script generation | Next steps

Rendered fromgetting-started.Rmdusingknitr::rmarkdown

Last update: 2026-06-25
Started: 2026-06-25

Mathematical overview of variance-based methods

Mathematical derivation | Computation of variance-based sensitivity indices | Homma & Saltelli (Sobol) | EFAST | References

Rendered fromvariance-based-methods.Rmdusingknitr::rmarkdown

Last update: 2026-06-25
Started: 2026-06-25

Midazolam DDI example

Background | Parameters analyzed | Loading the package and simulations | Specifying the input parameters | Specifying the model output | Running the sensitivity analyses | Interpreting the results

Rendered frommidazolam-ddi.Rmdusingknitr::rmarkdown

Last update: 2026-06-25
Started: 2026-06-25

UV filter formulation example

Parameters analyzed | Loading the package and simulation | Specifying the input parameters | Specifying the model output | Running the sensitivity analyses | Interpreting the results

Rendered fromuv-filter-formulation.Rmdusingknitr::rmarkdown

Last update: 2026-06-25
Started: 2026-06-25

Citation

Development and contributors

Readme and manuals

Help Manual

Help page	Topics
distribution	distribution
generateEFASTBarGraph	generateEFASTBarGraph
generateMorrisPlot	generateMorrisPlot
generateSobolBarGraph	generateSobolBarGraph
generateTornadoPlot	generateTornadoPlot
Generate Response Surface Contour Plots for eFAST Results	getContourPlot
LogNormalDistribution	LogNormalDistribution
LogUniformDistribution	LogUniformDistribution
NormalDistribution	NormalDistribution
runEFAST	runEFAST
runGUI	runGUI
runMorris	runMorris
runSobol	runSobol
runSU	runSU
SAOutput	SAOutput
SAParameter	SAParameter
UniformDistribution	UniformDistribution

Usage by other packages (reverse dependencies)